Misoprostol is commonly known as cytotec, which is typically used with mifepristone to bring about to end an abortion. This medication has the capability to work 95% effectively within the first 50 days of pregnancy. It can also be effective in the second trimester without causing any complications. It was developed back in 1980 and became popular ever since then. Various manufactures have set their hands on this medication causing it to have multiple trading names in the market. For instance, Mifeprex and Korlym etc.
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It works by blocking the body's natural production of a hormone (progesterone) that is required to maintain a pregnancy.
How does Misoprostol work?
Misoprostol is an artificial made steroid that hampers with the development of progesterone, a hormone that is essential to the progress of pregnancy. By stopping the development of progesterone the stimulate the escalation of the uterine lining which nourishes the evolving embryo (fetus). This leads to suppressing the normal utrine contractions which eject the embryo growing on the uterine wall. It fills the chemoreceptor are which are normally reserved for progesterone, but doesn't allow it to disseminate the progesterone signal. Failure to receive the signal, the body closes all formation of the uterus and inaugurates the normal menstrual process. The embryo bereaved of nutrients separates from the uterine wall and gets flushed out of the body.
What are Misoprostol advantages?
Misoprostol is given to a woman who is pregnant and wants to have an abortion without further ado. Where, the same woman would need to wait until the 12th week before she can have a vacuum aspiration abortion.
- It is a non-surgical method, no anesthesia or damages are caused the cervix as no surgical instruments are required in the process. It puts women at no risk of perforation.
- It provides more psychological control to the woman over the termination of her pregnancy. This way also appears similar to that of a miscarriage as there is less physical contact made.
- Misoprostol make the procedure of abortion more secluded.
- Misoprostol has the potential to make abortion more accessible in early gestation (50 days from pregnancy). Furthermore, it is way cheaper and less arduous than a surgical abortion.
How are Misoprostol administered?
- Firstly a medical examination must be done to confirm the pregnancy (ultrasound). The optimum time should be checked whether the medication can be ingested.
- If everything within the check turn up meeting the criteria, misoprostol can be consumed (it's usually three pills of 200 mcg each). However, if any complication or problems arise the dosages may be either increased or decreased.
- After 24 – 72 hours prior to the consumption of cytotec, Misoprostol (or similiar medication with different marketing names) must be consumed either orally, buccally or vaginally. (It's again two pills of 200mg each). However, they may differentiate in different cases as aforementioned. This completes the entire procedure.
- The woman should consider visiting the clinic for an examination or to report any side effects if any should arise. Let's make one thing clear, (bleeding and cramping) isn't a side effect it the after-effect of consuming the pill.
What are Misoprostol side effects?
Roughly all women using misoprostol undergo uterine cramping, vaginal bleeding or spotting, and abdominal pain. This takes place for an average of 9-16 days. The other side effects that are prevalent are: -
- regurgitating (vomiting)
- revulsion (nausea)
- diarrhea (loose bowels)
- lethargy (fatigue)
- dizziness (light-headedness)
Women in some cases may experience bleeding up to 30 days or more. RU-486 (mifepristone is contraindicated in the existence of ectopic pregnancy, hemorrhagic disorders, anticoagulant or long-term corticosteroid therapy, adrenal failure, inherited porphyria or an intrauterine device.